The San Francisco 49ers will welcome back wide receiver Deebo Samuel, who has missed most of the past three games with a shoulder injury, for their game against the Jacksonville Jaguars. Left tackle Trent Williams is also expected to return, but his status is more uncertain due to an ankle injury. Samuel's return is crucial for the offense, as they have struggled without him, averaging fewer points per game and fewer yards per play. Williams' return would also be a boost, especially for the run game, where the team has struggled in his absence.

• Deebo Samuel will return for the 49ers' game against the Jaguars after missing most of the past three games with a shoulder injury.
• Trent Williams is listed as questionable for the game, but his status is uncertain due to an ankle injury.
• The offense has struggled without Samuel, averaging fewer points and yards per play.
• Williams' return would be a boost for the run game, which has struggled in his absence.