The San Francisco 49ers have officially ruled out tight end George Kittle for their upcoming game against the Los Angeles Rams due to a hamstring injury. Kittle's absence, along with that of running back Christian McCaffrey and receiver Deebo Samuel, will challenge the 49ers' offensive strategy. Tight end Eric Saubert is expected to step in for Kittle, while the team also elevated Brayden Willis and defensive end Sam Okuayinonu from the practice squad for added depth.
- George Kittle's injury significantly impacts the 49ers' offensive capabilities.
- Eric Saubert is expected to take on a larger role in Kittle's absence.
- The 49ers are also missing key players like Christian McCaffrey and Deebo Samuel.