The Houston Texans are facing injury challenges in their backfield as Joe Mixon remains sidelined with an ankle injury, being labeled as 'week to week' by head coach Demeco Ryans. Meanwhile, Dameon Pierce is limited but expected to return for the upcoming game against the New England Patriots. Fantasy owners should be cautious about including Houston's running backs in their lineups for Week 6.
- Joe Mixon is unlikely to play this week, making him a risky option for fantasy owners.
- Dameon Pierce's limited practice indicates he might return, but caution is advised for fantasy lineups.
Joe Mixon | RB

Injury
Week 6
- Remains sidelined due to an ankle injury.
- Labeled as 'week to week' by head coach.
Dameon Pierce | RB

Pickup
Week 6
- Limited in practice but expected to return for Week 6.
- Fantasy owners should be cautious about relying on the backfield.
Houston Texans

- Facing injury issues in the running back position.
- Fantasy owners should avoid the backfield in Week 6.